Omidria

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Omeros

Omidria (phenylephrine and ketorolac injection) 1%/0.3% is added to ophthalmic irrigation solution used during cataract surgery or intraocular lens replacement and is indicated for maintaining pupil size by preventing intraoperative miosis and reducing postoperative ocular pain.

Description

At-a-Glance

Mechanism of Action: Ketorolac is a non-steroidal anti-inflammatory drug that inhibits both cyclooxygenase enzymes (COX-1 and COX-2), resulting in a decrease in tissue concentrations of prostaglandins to reduce pain due to surgical trauma. Ketorolac prevents surgically induced miosis by inhibiting prostaglandin synthesis secondary to ocular surgical insult or direct mechanical stimulation of the iris. Phenylephrine is an α1-adrenergic receptor agonist and, in the eye, acts as a mydriatic agent by contracting the radial muscle of the iris, resulting in pupil dilation. (According to the package insert)

Details

FDA

Yes

CE Mark

Not specified

Active Ingredients

Ketorolac/Phenylephrine

Application

Added to irrigation solution

Status

Prescription

Strength

1%/0.3%

In the News

Omeros Corporation Initiates Sales of Omidria in Europe »

Eyewire | 07.23.18