Compare Cross-Linking

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At-a-Glance

Description

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Active Ingredients

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  • Mechanism of Action: It is believed that lysyl oxidases, a family comprising LOX and four LOX-like enzymes (LOXL1-4), catalyze the formation of collagen crosslinks and elastin and are implicated in the age-related corneal stiffening synonymous with keratoconus.
  • Dosage: One drop twice per day.

IVMED-80 is the first eye-drop, non-surgical, non-laser treatment for medical crosslinking of the cornea. The FDA granted orphan drug designation for IVMED-80 for the treatment of keratoconus in November 2017.

Orphan Drug Designation

Not specified

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Topical

Prescription

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