Lotemax Gel | Beye

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Lotemax Gel

Lotemax Gel

Bausch + Lomb Inc.

Lotemax (loteprednol etabonate ophthalmic gel) 0.5% is a corticosteroid in a gel formulation indicated for the treatment of postoperative inflammation and pain following ocular surgery.

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At-a-Glance

Mechanism of Action: Corticosteroids inhibit the inflammatory response to a variety of inciting agents and probably delay or slow healing. They inhibit the edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, fibroblast proliferation, deposition of collagen, and scar formation associated with inflammation. While glucocorticoids are known to bind to and activate the glucocorticoid receptor, the molecular mechanisms involved in glucocorticoid/glucocorticoid receptor-dependent modulation of inflammation are not clearly established. However, corticosteroids are thought to inhibit prostaglandin production through several independent mechanisms.
Dosage: One to two drops of LOTEMAX into the conjunctival sac of the affected eye four times daily beginning the day after surgery and continuing throughout the first 2 weeks of the postoperative period.

Details

FDA

Yes

CE Mark

Not specified

Active Ingredients

Loteprednol etabonate

Application

Topical

Status

Prescription

Strength

0.5%

From Your Peers

We managed this patient’s significant DED aggressively using warm compresses, LipiFlow thermal pulsation treatment (Johnson & Johnson), loteprednol 0.5% four times daily, lifitegrast 5.0% (Xiidra; Shire), and artificial tears. One cannot perform premium cataract surgery using premium lenses without ensuring a premium ocular surface. Paying attention to ocular surface health is the most important thing surgeons can do to improve their outcomes."

Lessons from the PHACO Study

Eric D. Donnenfeld, MD

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If there is significant inflammation of the ocular surface, I add a low-dose topical steroid, loteprednol etabonate ophthalmic suspension 0.5% twice a day, and lifitegrast ophthalmic solution 5% (Xiidra; Shire)."

Bye Bye, Dry Eye

Gregg J. Berdy, MD, FACS

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My Algorithm for DED

My Algorithm for DED

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Company Information

Contact the company for additional information, availability, or pricing:

Bausch + Lomb Inc.

bausch.com

400 Somerset Corporate Blvd.

Bridgewater, NJ 08807

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